Aggressive Cancer Research

Aggressive Cancer Research

The National Cancer Center created the Aggressive Cancer Research project in 2015 to provide additional funding for this important and pressing area of cancer research.

Our Icahn School of Medicine at Mt. Sinai funding grant provides research whose goal is the development of strategies aimed at blunting the very essence of cancer. This in turn can lead to the improvement of current therapies for highly aggressive cancers whose chemotherapeutic regimens often result in high toxicity for patients, treatments that are difficult for patients to tolerate.

Aggressive Cancer Research

Current Grants and Renewals

National Cancer Center has been proud to award grants to many fine research organizations. We know that a cure lies in research and we are committed to supporting as many research projects as we can.

Sydney Moyer, Ph.D.

Dana-Farber Cancer Institute, Boston MA

PROJECT: Th1 cells with increased adhesion pathway expression are required for inflammation-associated colorectal cancer development and progression

NEW GRANT

Lizhong Ding, Ph.D.

The University of California, Los Angeles

PROJECT: Liver specific fibrosis drives immunosuppression in metastatic melanoma

RENEWAL

Audifas Salvador Matus Meza, Ph.D.

Univ of Nebraska Medical Center, Omaha, NE

PROJECT: Development of an NTSR1-targeted Radiotherapeutic for Colorectal Cancer and Other NTSR1-positive Cancers

RENEWAL

Past Beneficiaries

William Maguire, M.D., Ph.D.

Univ of Pittsburgh, Pittsburgh, PA

PROJECT: Biomarkers of sulforaphane for therapeutic prevention of melanoma

2021-2022

Chiwei Xu, Ph.D.

The Rockefeller Univ, New York, NY

PROJECT: Crosstalk between epithelial stem cells and peripheral nerves in cancer

2021-2022

Manqi Zhang, Ph.D.

Duke University, Durham, NC

PROJECT: Loss of ALK4 promotes EMT through regulation of Golgi-mediated receptor glycosylation in pancreatic cancer

2021-2022

Yuanyuan Xie, Ph.D.

Regents of the Univ of Colorado

PROJECT: Elucidating the functional and genomic impact of retrocopies on cancer

2019-2021

Siva Karthik Varanasi, PhD.

Salk Inst for Biological Studies

PROJECT: Evaluating the role of bile acids as a metabolic checkpoint of anti-tumor T cell Hepatocellular Carcinoma

2019-2021

Manoela Tiago dos Santos, Ph.D.

Thomas Jefferson University, Philadelphia, PA

PROJECT: BET inhibition to optimize BRAFi/MEKi therapy for mutant BRAF
2019-2020

Zhentao Yang, PhD.

UCLA Division of Dermatology

PROJECT: Immune evasion mechanisms during MAPK inhibitor therapy in melanoma
2018

Jin Qian, M.D., PhD.

UCLA Division of Dermatology

PROJECT: Immune evasion mechanisms during MAPK inhibitor therapy in melanoma
2017

Nishana Mayilaadumveettil, Ph.D.

NYU School of Medicine

PROJECT:Role of CTCF Mutations in Altering Nuclear Architecture and Gene Regulation in Cancer
2017-2018

Gabriele Varano, Ph.D.

Icahn School of Medicine at Mt Sinai, NY

PROJECT: Cellular determinants of genetic heterogeneity during MYC-driven B cell lymphomagenesis
2016-2017

Elaine Bich Than, Ph.D.

Weill Medical College of Cornell University, NY

PROJECT: The role of the microbiome and butyrate in CpG Island Methylator Phenotype colorectal cancer
2015

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2023 New and Renewed Research Grants

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2023 Grants

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Total Grand Funding To Date