Our Programs

Aggressive Cancer Research

Our Icahn School of Medicine at Mt. Sinai funding grant provides research whose goal is the development of strategies aimed at blunting the very essence of cancer. This in turn can lead to the improvement of current therapies for highly aggressive cancers whose chemotherapeutic regimens often result in high toxicity for patients, treatments that are difficult for patients to tolerate.

Current Grant: Manoela Tiago dos Santos, Ph.D.
PROJECT: BET inhibition to optimize BRAFi/MEKi therapy for mutant BRAF

The Breast Cancer Project

Our grant to Duke University Medical Center in Durham, NC, funds research into breast cancer genetics and is geared to making existing approaches more effective in the prevention, detection and treatment of breast cancer. This project addresses issues at the cutting edge of cancer immunotherapy.

Current Grant: Polina Vaitsenfeld, Ph.D.
PROJECT: Enhancing antibody-mediated immunity against tumor-associated carbohydrate antigens

The Children's Cancer Project

Fullfilling the National Cancer Center’s desire to provide funds for pediatric cancer research and education, we created the Children’s Cancer Project to investigate prevention and treatment of pediatric oncology, as well as public education relating to detection.

Our fellowship to Children’s Hospital of Philadelphia focuses on neuroblastoma, the most common solid tumor cancer found in children.

Current Grant: Yuanyuan Li, Ph.D.
PROJECT: IRAK1 Kinase drives cell survival in response to ionizing radiation and defines a target to overcome intrinsic tumor radioresistance

Fighting Childhood Leukemia

The Fighting Childhood Leukemia program of the National Cancer Center provides research funding for the most common form of cancer in children. Research funded at Harvard’s Dana-Farber Cancer Institute seeks to discover novel molecular markers and potential therapeutic targets that, in time, can lead to improved diagnosis and prognosis of acute myeloid leukemia patients.

Current Grant: Darko Barisic, Ph.D.
PROJECT: Role of chromatin remodeling complex BAF in lymphomagenesis

NCC Special Programs

In addition to our four earmarked primary research funding programs, NCC fellowships have also funded research showing particular promise in the following areas: brain tumors, melanoma, DNA repair, anti-cancer therapies, gene mutations and targeted therapeutics. Grants have included:

Renewal Grant: Vivian Chua
PROJECT: Improving therapeutic options for metastatic uveal melanoma (UM)

Current Grant: Manoela Tiago dos Santos, Ph.D.
PROJECT: BET inhibition to optimize BRAFi/MEKi therapy for mutant BRAF

Current Grant: Yuanfan Yang, M.D.
PROJECT: Anti-tumor efficacy of EGFR-targeting immuntoxin in combination with CCNU or PD-L1 blockade for glioma